Oxidized cellulose
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Oxidized cellulose is a water-insoluble derivative of cellulose. It can be produced from cellulose by the action of an oxidizing agent, such as chlorine, hydrogen peroxide, peracetic acid, chlorine dioxide, nitrogen dioxide, persulfates, permanganate, dichromate-sulfuric acid, hypochlorous acid, hypohalites or periodates and a variety of metal catalysts.[1] Oxidized cellulose may contain carboxylic acid, aldehyde, and/or ketone groups, in addition to the original hydroxyl groups of the starting material, cellulose, depending on the nature of the oxidant and reaction conditions.[2]
It is an antihemorrhagic.[3] It works both by absorbing the blood (similar to a cotton ball)[4] and by triggering the contact activation system. It is poorly absorbed and may cause healing complications postoperatively.[5]
See also
- Regenerated cellulose
References
- .
- ^ US 5780618, Banker GS, Kumar V, "Oxidized cellulose", issued 14 July 1998, assigned to Biocontrol Inc.
- PMID 10350276.
- ^ "Oxidised Cellulose". Advanced Medical Solutions Group plc. 30 November 2023.
- ISBN 978-0-323-37580-1.