Partial agonist
In
competitive antagonist,[citation needed] competing with the full agonist for receptor occupancy and producing a net decrease in the receptor activation observed with the full agonist alone.[1] Clinically, partial agonists can be used to activate receptors to give a desired submaximal response when inadequate amounts of the endogenous ligand are present, or they can reduce the overstimulation of receptors when excess amounts of the endogenous ligand are present.[2]
Some currently common drugs that have been classed as partial agonists at particular receptors include
CB1
and CB2 receptors, with the former being responsible for its psychoactive effects.
See also
- Competitive antagonist
- Intrinsic sympathomimetic activity of beta blockers
- Inverse agonist
- Mixed agonist/antagonist
References
 | This pharmacology-related article is a stub. You can help Wikipedia by expanding it. |