Tandemly arrayed genes
Tandemly arrayed genes (TAGs) are a
tandem duplications,[1] a process in which one gene is duplicated and the copy is found adjacent to the original.[2] They serve to encode large numbers of genes
at a time.
TAGs represent a large proportion of genes in a genome, including between 14% and 17% of the human, mouse, and rat genomes.ribosomes, and cell number doubles within 24 hours. In order to provide the necessary ribosomes, multiple RNA polymerases must consecutively transcribe multiple rRNA genes.[3]
In some species, such as Arabidopsis thaliana and Oryza sativa, most TAGs are the result of unequal chromosomal crossover during genetic recombination.[4]
See also
- Satellite DNA
- Tandem repeats
Notes
- ^ Pan & Zhang 2008.
- ^ a b c Lajoie, Bertrand & El-Mabrouk 2007, p. 96.
- ISBN 9781429234139.
- ^ Barker, Baute & Liu 2012, p. 157.
References
- Barker, Michael S.; Baute, Gregory J.; Liu, Shao-Lun (5 March 2012). "Duplications and Turnover in Plant Genomes". In Wendel, Jonathan F.; Greilhuber, Johann; Dolezel, Jaroslav; et al. (eds.). Plant Genome Diversity Volume 1: Plant Genomes, their Residents, and their Evolutionary Dynamics. Plant Genome Diversity. Vol. 1. Springer Science & Business Media. pp. 155โ169. ISBN 9783709111307.
- Pan, Deng; Zhang, Liqing (2008). "Tandemly arrayed genes in vertebrate genomes". International Journal of Genomics. 2008. Hindawi Publishing Corporation: 545269. PMID 18815629.
- Lajoie, Mathieu; Bertrand, Denis; El-Mabrouk, Nadia (16โ18 September 2007). "Evolution of tandemly-arrayed genes in multiple species". In Tesler, Glenn; Durand, Dannie (eds.). Comparative Genomics: RECOMB 2007, International Workshop, RECOMB-CG 2007, San Diego, CA, USA, September 16โ18, 2007, Proceedings. RECOMB 2007, International Workshop, RECOMB-CG 2007. Lecture Notes in Bioinformatics. Vol. 4751. ISSN 0302-9743.
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