Thymidine triphosphate

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Thymidine triphosphate
Skeletal formula of thymidine triphosphate, 3- negative charge
Space-filling model of the thymidine triphosphate molecule, 4- negative charge
Names
IUPAC name
Thymidine 5′-(tetrahydrogen triphosphate)
Systematic IUPAC name
O1-{[(2R,3S,5R)-5-(2,4-Dioxo-5-methyl-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxyoxolan-2-yl]methyl} tetrahydrogen triphosphate
Other names
dTTP, 2′-Deoxythymidine triphosphate
Identifiers
3D model (
JSmol
)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard
 100.006.064 Edit this at Wikidata
IUPHAR/BPS
MeSH thymidine+5'-triphosphate
UNII
  • CC1=CN(C(=O)NC1=O)C2CC(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O
Properties
C10H17N2O14P3
Molar mass 482.168
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Thymidine triphosphate (TTP), also called deoxythymidine triphosphate (dTTP),[1] is one of the four

deoxyribonucleoside triphosphates, thymidine triphosphate does not always contain the "deoxy" prefix in its name.[2] The corresponding ribonucleoside triphosphate is called uridine triphosphate
.

It can be used by DNA ligase to create overlapping "sticky ends" so that protruding ends of opened microbial plasmids may be closed up.

References

  1. ^ "Thymidine 5'-triphosphate (PAMDB000346)". University of Maryland, Baltimore. 2018-01-22. Archived from the original on 2023-10-29. Retrieved 2023-10-29.
  2. ISBN 978-0-8412-3999-9
    .


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