Traditional serrated adenoma
Traditional serrated adenomas | |
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Traditional serrated adenoma with intermediate magnification, showing serrated crypts and cytologic atypia (H&E stain). | |
Specialty | Gastroenterology |
Symptoms | Asymptomatic |
Complications | Colorectal cancer |
Usual onset | >50 years of age |
Diagnostic method | Colonoscopy |
Treatment | Polypectomy |
Frequency | <1% of all colon polyps |
Traditional serrated adenoma is a
colon, often in the distal colon (sigmoid, rectum). Traditional serrated adenomas are a type of serrated polyp, and may occur sporadically or as a part of serrated polyposis syndrome. Traditional serrated adenomas are relatively rare, accounting for less than 1% of all colon polyps.[1][2] Usually, traditional serrated adenomas are found in the distal colon and are usually less than 10 mm in size.[1]
Histopathology
Traditional serrated adenomas are characterized by ectopic crypts, pseudostratification, and a villous pattern with stretched nuclei.[3]
Epidemiology
Usually found in individuals over the age of 50 years, traditional serrated adenomas affect men and women equally.[1] The overall prevalence of traditional serrated adenomas is less than 1% of the general population.[3] Traditional serrated adenomas are the least common type of serrated polyps found in the colon, accounting for 5% of serrated colon polyps.[4]