Centromedian nucleus
| Centromedian nucleus | |
|---|---|
| Details | |
| Part of | Intralaminar thalamic nuclei |
| Identifiers | |
| Latin | nucleus centromedianus thalami |
| Acronym(s) | CM or Cm-Pf |
| NeuroNames | 323 |
| NeuroLex ID | birnlex_805 |
| TA98 | A14.1.08.618 |
| FMA | 62165 |
| Anatomical terms of neuroanatomy | |
In the anatomy of the brain, the centromedian nucleus, also known as the centrum medianum, (CM or Cm-Pf) is a part of the intralaminar thalamic nuclei (ITN) in the thalamus. There are two centromedian nuclei arranged bilaterally.
In humans, it contains about 2000 neurons per cubic millimetre and has a volume of about 310 cubic millimetres with 664,000 neurons in total.[1]
Input and output
It sends
nerve fibres to the subthalamic nucleus and putamen.[2] It receives nerve fibres from the cerebral cortex, vestibular nuclei, globus pallidus, superior colliculus, reticular formation, and spinothalamic tract
.
Function
Its physiological role involves
mutism and severe delirium. Unilateral lesions can lead to unilateral thalamic neglect
.
A patient with
electrodes implanted into more than 50 different regions in his brain (including regions giving him orgasmic feelings) choose to self stimulate the electrode in his centromedian nucleus more than all other electrodes. The patients explanation of this: "The subject reported that he was almost able to recall a memory during this stimulation, but he could not quite grasp it. The frequent selfstimulations were an endeavor to bring this elusive memory into clear focus."[4]
Additional images
-
Thalamus -
Thalamus
Notes and references
- PMID 10869053. Archived from the originalon 2004-12-25. Retrieved 2004-09-24.
- PMID 4962197.
- PMID 32023343.
- )
External links
- Illustration and text: coro97/contents.htm at the University of Wisconsin-Madison Medical school - The Global Thalamus (See level 12, the centromedian nucleus is labelled CM)
- Schiff N, Plum F (2000). "The role of arousal and "gating" systems in the neurology of impaired consciousness". Journal of Clinical Neurophysiology. 17 (5): 438โ52. S2CID 17983908.
- Joe Bogen's Consciousness Page (Professor Bogen) at California Institute of Technology
- NIF Search - Centromedian Nucleus[permanent dead link] via the Neuroscience Information Framework
