Doramectin

Source: Wikipedia, the free encyclopedia.
Doramectin
Clinical data
Trade namesDectomax, others
Other names
  • 25-cyclohexylavermectin B1,
  • 25-cyclohexyl-25-de(l-methylpropyl)avermectin B1a,
  • 25-cyclohexyl-5-O-demethyl-25-de(l-methylpropyl)avermectin A1a
AHFS/Drugs.comInternational Drug Names
License data
QP54AA03 (WHO)
Legal status
Legal status
Identifiers
  • (1'R,2S,4'S,5S,6R,8'R,10'E,12'R,13'S,14'E,20'R,21'R,24'S)-6-cyclohexyl-21',24'-dihydroxy-12'-{[(2R,4S,5S,6S)-5-{[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-4-methoxy-6-methyloxan-2-yl]oxy}-5,11',13',22'-tetramethyl-5,6-dihydro-3',7',19'-trioxaspiro[pyran-2,6'-tetracyclo[15.6.1.14,8.020,24]pentacosane]-10',14',16',22'-tetraen-2'-one
ECHA InfoCard
100.123.125 Edit this at Wikidata
Chemical and physical data
FormulaC50H74O14
Molar mass899.128 g·mol−1
  • InChI=1S/C50H74O14/c1-27-13-12-16-34-26-57-47-42(51)30(4)21-37(50(34,47)54)48(53)60-36-22-35(63-49(25-36)20-19-29(3)45(64-49)33-14-10-9-11-15-33)18-17-28(2)44(27)61-41-24-39(56-8)46(32(6)59-41)62-40-23-38(55-7)43(52)31(5)58-40/h12-13,16-17,19-21,27,29,31-33,35-47,51-52,54H,9-11,14-15,18,22-26H2,1-8H3/b13-12+,28-17+,34-16+/t27-,29-,31-,32-,35+,36-,37-,38-,39-,40-,41-,42+,43-,44-,45-,46-,47+,49+,50+/m0/s1 checkY
  • Key:QLFZZSKTJWDQOS-YDBLARSUSA-N checkY
  (verify)

Doramectin, sold under the brand name Dectomax among others, is a

generic medication.[3] It is available as a combination with levamisole under the brand name Valcor.[4]

It is used for the treatment and control of internal parasitosis (gastrointestinal and pulmonary nematodes), ticks and mange (and other ectoparasites). Doramectin is a derivative of

topical solution.[1][2]

Society and culture

Brand names

Doramectin is marketed in other countries as Doramec L.A. for cattle, sheep, and swine.

Doramectin is available for horses as an oral, flavored, bioadhesive gel under the name Doraquest L.A. Oral Gel. It can be used to control and treat internal parasites as roundworms, lungworms and some external parasites.

References

  1. ^ a b c d "Dectomax- doramectin injection, solution". DailyMed. 13 September 2022. Retrieved 25 January 2023.
  2. ^ a b c d "Dectomax Pour-On- doramectin solution". DailyMed. 5 August 2022. Retrieved 25 January 2023.
  3. ^ a b "FDA Approves First Generic Doramectin for Use in Cattle". U.S. Food and Drug Administration (FDA). 11 January 2023. Retrieved 25 January 2023.
  4. ^ "Animal Drugs @ FDA". animaldrugsatfda.fda.gov. Retrieved 25 January 2023.
  5. PMID 8236738
    .
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