Hippocampal sulcus

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Hippocampal sulcus
Hippocampal sulcus labeled at center.
Details
Identifiers
Latinsulcus hippocampalis,
sulcus hippocampi
NeuroNames42
NeuroLex IDbirnlex_4004
TA98A14.1.09.236
TA25522
FMA83747
Anatomical terms of neuroanatomy

The hippocampal sulcus, also known as the hippocampal fissure, is a sulcus that separates the dentate gyrus from the subiculum and the CA1 field in the hippocampus.

Structure

Development

Hippocampal sulcus remnants seen on T2-weighted axial MRI image.

During human

cornu ammonis. After about 18 weeks, the walls of the fissure fold into each other and begin to fuse. By 30 weeks, the hippocampal sulcus is normally obliterated except for its most medial part, leaving a shallow surface indentation.[1]

Clinical significance

Enlargement of the hippocampal sulcus has been associated with medial temporal lobe atrophy occurring in Alzheimer's disease.[2]

See also

References

  1. ^ Humphrey, Tryphena. "The development of the human hippocampal fissure". Journal of anatomy. 1967 September; 101(Pt 4): 655–676.
  2. PMID 17110684
    .