Ovarian tumor

Source: Wikipedia, the free encyclopedia.
Gross pathology of an ovarian carcinoma.

Ovarian tumors, or ovarian neoplasms, are tumors arising from the ovary. They can be benign or malignant (ovarian cancer). They consist of mainly solid tissue, while ovarian cysts contain fluid.

Histopathologic classification

Ovarian tumors by incidence and risk of ovarian cancer[1]
Further information: Ovarian cancer

Ovarian tumors are classified according to the histology of the tumor, obtained in a pathology report. Histology dictates many aspects of clinical treatment, management, and prognosis.

The most common forms are:

Type Subtype Relative incidence[2] Percent malignant[2] Comments Micrograph
Germ cell tumor Mature cystic teratoma 46.0% 0.17% to 2%[3] Cystic, with elements of all 3 germ layers (endoderm, mesoderm and ectoderm).[4]
Hair follicles.
Immature teratoma 2.5% 100% A
anaplastic immature elements, and is often synonymous with malignant teratoma.[5]
Other germ cell tumors 3.0% Others mainly include
squamous cell carcinoma arising from a dermoid cyst, and malignant mixed germ cell tumor.[2]
Surface epithelial-stromal tumor Serous tumor 25% 18.5% Benign serous tumors of the right ovarian cyst are thinwalled unilocular cysts that are lined by ciliated pseudostratified cuboidal or columnar epithelium.[6]
Mucinous tumor 15% 8.8% Benign mucinous tumors of the ovary consist of simple, nonstratified columnar epithelium with basally-located hyperchromatic nuclei and resemble gastric foveolar epithelium.[6]
Endometrioid tumor 1% Almost 100% Tubular glands, resembling endometrium.[7]
Other surface-epithelial tumors 1.5% Others include mainly malignant mixed
Brenner tumor and mixed epithelial tumor.[2]
Brenner tumor
.
Sex cord-stromal tumor
 Ovarian fibroma 1.5% 0%
Spindle-shaped fibroblastic cells and abundant collagen.[8]
Adult granulosa cell tumor 1% Almost 100% Small, bland, cuboidal to polygonal cells in various patterns.[9]
Other sex cord-stromal tumors 1% Others include mainly
juvenile granulosa cell tumor, thecoma and sclerosing stromal tumor[2]
Secondary/metastatic) tumor 2% 100% Usually from
colon cancer, endometrial cancer, stomach cancer or cervical cancer.[10]

Mixed tumors contain elements of more than one of the above classes of tumor histology.

History

An 1882 article appearing in Scientific American mentions the case of a patient at University of Pennsylvania Hospital when Dr. William Goodell removed a 112 lbs tumor from a 31 year old patient, who weighted 75 lbs after removal from the tumor.[11]

See also

References

  1. PMID 23082264
    .
  2. ^
    ISSN 2091-0908
    .
  3. PMID 23082264
    .
  4. ^ Hillary Rose Elwood. "Skin nonmelanocytic tumor - Other tumors of skin - Benign (mature) cystic teratoma". pathology Outlines. Topic Completed: 1 November 2016. Revised: 4 April 2019
  5. PMID 31039746
    .
  6. ^
    PMID 29744056
    .
  7. ^ Shahrzad Ehdaivand. "Ovary tumor - Endometrioid tumors - General". Pathology Outlines. Topic Completed: 1 December 2012. Revised: 6 March 2020
  8. PMID 27821988
    .
  9. ^ Shahrzad Ehdaivand. "Ovary tumor - Sex cord stromal tumors - Granulosa cell tumor - adult". Pathology Outlines. Topic Completed: 1 December 2012. Revised: 9 March 2020
  10. ^ Lisa Lee-Jones, University of Wales College of Medicine (2003-12-01). "Ovarian tumours : an overview". Atlas of Genetics and Cytogenetics in Oncology and Haematology.
  11. ^ Scientific American. Munn & Company. 1882-02-25. p. 114.
Retrieved from "https://en.wikipedia.org/w/index.php?title=Ovarian_tumor&oldid=1194577674"