Adenomatoid tumor
Adenomatoid tumor | |
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High-magnification micrograph of an adenomatoid tumor. H&E stain. | |
Specialty | Oncology ![]() |
Adenomatoid tumors are rare and
Pathology
While adenomatoid tumors are present in both the various body areas of males and females, one study discovered that these tumors were more likely to occur in Caucasian males. Adenomatoid tumors can be found in a widespread age of people ranging from 18 to 79 years old.[3] Most of these tumors are not spotted until about the 30s. This asymptomatic nature is due to the fact that a majority of adenomatoid tumors grow silently and are sometimes dormant without causing any pain. This is what contributes to the difficulty of catching adenomatoid tumors.
These benign tumors can grow up to 5.0 centimeters (most of them range around to 2.0 cm). Although adenomatoid tumors are not known to infiltrate surrounding tissues, it is possible that there are multiple adenomatoid tumors in the same area.
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An adenomatoid tumor of the fallopian tube, low magnification, displaying infiltrative-like borders.
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High magnification of the same case, showing the typical[9] features of tubular spaces of varying size composed of flattened cells resembling endothelium.
Ancillary Studies
Immunohistochemistry
Given their mesothelial origin, the cells lining the spaces are positive for cytokeratins,
Molecular analysis
Adenomatoid tumors of the female and male genital tract are characterized by somatic missense mutations in the TRAF7 gene, which leads to aberrant
Imaging
In order to see adenomatoid tumors multiple imaging modalities are used. These tumors appear to be small, solid, and circumscribed with a color that usually ranges from white to tan.[6]
Treatment
If located in the testes region, removal of the tumor must be handled with great care to prevent damage to testosterone production and keep the patient fertile. If removal of the tumor is necessary then an excision biopsy is usually done on the patient. Though this can be used as both a diagnostic and removal procedure, it has proven to be effective. Successful procedures results in a tumor free area that is not prone recur.[6]
When used as a diagnosis tool, the excision biopsy can collect a tissue sample from the tumor. Through histological evaluation the lesion can be categorized in the patients.
Additional images
![](http://upload.wikimedia.org/wikipedia/commons/thumb/e/e2/Adenomatoid_epidi_0001.jpg/220px-Adenomatoid_epidi_0001.jpg)
References
- PMID 15072910.
- ^ "Adenomatoid tumor of the epididymis". Archived from the original on 2007-06-15. Retrieved 2007-12-15.
- ^ a b "Adenomatoid Tumor - American Urological Association". www.auanet.org. Archived from the original on 2020-07-16. Retrieved 2020-04-24.
- PMID 20462987.
- PMID 12808068.
- ^ PMID 21151545.
- S2CID 39868984.
- ^ "Testicular Adenomatoid Tumor Pathology: Definition, Epidemiology, Etiology". 2019-11-26.
- ^ Nicole Riddle, Jamie Shutter. "Fallopian tubes & broad ligament - Fallopian tube tumors - Adenomatoid tumor". Pathology Outlines. Archived from the original on 2021-10-18. Retrieved 2020-10-16. Topic Completed: 1 September 2013. Minor changes: 13 December 2019
- ^ ISBN 978-0-323-35909-2.
- OCLC 934111854.
- PMID 15692945.