Sink condition
In pharmaceutics, sink condition is a term mostly related to the dissolution testing procedure.
It means using a sheer volume of
excipients) contained in the dosage form being tested.[1]
During the
dissolution rate will gradually begin to reduce in significant amounts, enough to corrupt the test results. .[2][3][4]
See also
- Absorption (pharmacokinetics)
- Dissolution testing
- Pharmaceutical formulation
- Tablet (pharmacy)
- Tablet hardness testing
References
- ^ "Shear Rate & Sink Conditions". LabHut. SMI-LabHut Ltd. Retrieved 17 April 2016.
- ISBN 978-1-4200-0955-2.
- ISBN 978-0-203-64447-8.
- ^ Remington Essentials of Pharmaceutics - Felton, Linda 2012: Remington Essentials of Pharmaceutics - Felton, Linda 2012. booksonline. pp. 65–66. GGKEY:KQQLT3XT7H1.
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