Thyroid adenoma
Thyroid adenoma | |
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Thyroid adenoma | |
Specialty | Oncology, endocrinology |
A thyroid adenoma is a benign tumor of the thyroid gland, that may be inactive or active (functioning autonomously) as a toxic adenoma.
Signs and symptoms
A thyroid adenoma may be clinically silent ("cold" adenoma), or it may be a functional tumor, producing excessive
Diagnosis
Morphology
Thyroid follicular adenoma ranges in diameter from 3 cm on an average, but sometimes is larger (up to 10 cm) or smaller. The typical thyroid adenoma is solitary, spherical and encapsulated lesion that is well demarcated from the surrounding parenchyma. The color ranges from gray-white to red-brown, depending upon
- the cellularity of the adenoma
- the colloid content.
Areas of hemorrhage, fibrosis, calcification, and cystic change, similar to what is found in multinodular goiters, are common in thyroid (follicular) adenoma, particularly in larger lesions.
Types
Almost all thyroid adenomata are follicular adenomata.
- Fetal (microfollicular) - these have the potential for microinvasion.[3] These consist of small, closely packed follicles lined with epithelium.[4]
- Colloid (macrofollicular) - these do not have any potential for microinvasion[3]
- Embryonal (atypical) - have the potential for microinvasion.[3]
- Hürthle cell adenoma (oxyphil or oncocytic tumor) - have the potential for microinvasion.[3]
- Hyalinizing trabecular adenoma[5]
Papillary adenomata are very rare.[3]
Differential diagnosis
A thyroid adenoma is distinguished from a
Careful
Management
Most patients with thyroid adenoma can be managed by
References
- ISBN 978-0-7216-0187-8.)
{{cite book}}
: CS1 maint: numeric names: authors list (link - ^ "Endocrine Pathology". Retrieved 2009-05-08.
- ^ a b c d e emedicine > Thyroid, Evaluation of Solitary Thyroid Nodule > Benign Thyroid Nodules By Daniel J Kelley and Arlen D Meyers. Updated: Oct 17, 2008
- ^ TheFreeDictionary > microfollicular adenoma Citing: Dorland's Medical Dictionary for Health Consumers. Copyright 2007
- PMID 21940281.
- PMID 21357288.
- ^ ISBN 978-0-7216-7335-6.
- ^
- PMID 32965923, retrieved 2020-11-07