Cripavirus
Appearance
Cripavirus | |
---|---|
Virus classification | |
(unranked): | Virus |
Realm: | Riboviria |
Kingdom: | Orthornavirae |
Phylum: | Pisuviricota |
Class: | Pisoniviricetes |
Order: | Picornavirales |
Family: | Dicistroviridae |
Genus: | Cripavirus |
Cripavirus is a genus of
viruses in the order Picornavirales, in the family Dicistroviridae. Invertebrates serve as natural hosts. There are four species in this genus. Diseases associated with this genus include: DCV: increased reproductive potential; extremely pathogenic when injected with high associated mortality; CrPV: paralysis and death.[1][2] These viruses can produce proteins directly from their RNA genome upon entering a cell; and therefore, does not require an RNA polymerase packaged in with it, as this may be produced from the genome after entering the cell.[3]
The name of the cripavirus family originates from its most famous member the Cricket Paralysis Virus.Cripavirus IRES. The Cripavirus IRES is an RNA element that allows the virus to bind the ribosome and translate without a need for any initiation factors[4]
– as initiation is the most regulated step of translation this allows the virus to avoid many mechanisms to inhibit viral activity.
Taxonomy
The genus contains the following species:[2]
Structure
Viruses in Cripavirus are non-enveloped, have
3' end has a series of A's near it. The genome has 2 open reading frames.[1]
Genus | Structure | Symmetry | Capsid | Genomic arrangement | Genomic segmentation |
---|---|---|---|---|---|
Cripavirus | Icosahedral | Pseudo T=3 | Non-enveloped | Linear | Monopartite |
Life cycle
Entry into the host cell is achieved by penetration into the host cell. Replication follows the positive stranded RNA virus replication model. Positive stranded rna virus transcription is the method of transcription. Translation takes place by viral initiation, and ribosomal skipping. Invertebrates serve as the natural host. Transmission routes are contamination.[1]
Genus | Host details | Tissue tropism | Entry details | Release details | Replication site | Assembly site | Transmission |
---|---|---|---|---|---|---|---|
Cripavirus | Invertebrates | None | Cell receptor endocytosis | Budding | Cytoplasm | Cytoplasm | Food |
References
- ^ a b c "Viral Zone". ExPASy. Retrieved 15 June 2015.
- ^ a b "Virus Taxonomy: 2020 Release". International Committee on Taxonomy of Viruses (ICTV). March 2021. Retrieved 20 May 2021.
- ^ a b International Committee on the Taxonomy of Viruses Archived 1 December 2008 at the Wayback Machine
- PMID 19632368