Geminiviridae
Geminiviridae | |
---|---|
Purified Maize streak virus (MSV) particles stained with uranyl acetate. Size bar indicates 50 nm. | |
Virus classification | |
(unranked): | Virus |
Realm: | Monodnaviria |
Kingdom: | Shotokuvirae |
Phylum: | Cressdnaviricota |
Class: | Repensiviricetes |
Order: | Geplafuvirales |
Family: | Geminiviridae |
Genera | |
Geminiviridae is a family of
Mastrevirus and curtovirus
These viruses are responsible for a significant amount of crop damage worldwide. Epidemics of geminivirus diseases have arisen due to a number of factors, including the recombination of different geminiviruses coinfecting a plant, which enables novel, possibly virulent viruses to be developed. Other contributing factors include the transport of infected plant material to new locations, expansion of agriculture into new growing areas, and the expansion and migration of vectors that can spread the virus from one plant to another.[5]
Virology
The genome of ssDNA can either be a single component between 2500–3100
Genus | Type Species | Structure | Symmetry | Capsid | Genomic arrangement | Genomic segmentation |
---|---|---|---|---|---|---|
Becurtovirus | Beet curly top Iran virus | Twinned Icosahedral | Incomplete T = 1 | Non-enveloped | Circular | Monopartite |
Begomovirus | Bean golden yellow mosaic virus | Twinned Icosahedral | Incomplete T = 1 | Non-enveloped | Circular | Segmented |
Capulavirus[6] | Euphorbia caput-medusae latent virus | Twinned Icosahedral | Incomplete T = 1 | Non-enveloped | Circular | Monopartite |
Curtovirus | Beet curly top virus | Twinned Icosahedral | Incomplete T = 1 | Non-enveloped | Circular | Monopartite |
Eragrovirus | Eragrostis curvula streak virus | Twinned Icosahedral | Incomplete T = 1 | Non-enveloped | Circular | Monopartite |
Grablovirus[7] | Grapevine red blotch virus | Twinned Icosahedral | Incomplete T = 1 | Non-enveloped | Circular | Monopartite |
Mastrevirus | Maize streak virus | Twinned Icosahedral | Incomplete T = 1 | Non-enveloped | Circular | Monopartite |
Topocuvirus | Tomato pseudo-curly top virus | Twinned Icosahedral | Incomplete T = 1 | Non-enveloped | Circular | Monopartite |
Turncurtovirus | Turnip curly top virus | Twinned Icosahedral | Incomplete T = 1 | Non-enveloped | Circular | Monopartite |
Taxonomy
The following genera are recognized:[3]
- Becurtovirus
- Begomovirus
- Capulavirus
- Citlodavirus
- Curtovirus
- Eragrovirus
- Grablovirus
- Maldovirus
- Mastrevirus
- Mulcrilevirus
- Opunvirus
- Topilevirus
- Topocuvirus
- Turncurtovirus
Several additional genera have been proposed: Baminivirus, Nimivirus and Niminivirus.[8]
Replication
Geminivirus genomes encode only a few proteins; thus, they are dependent on host cell factors for replication: these include factors such as
These viruses tend to be introduced into and initially infect differentiated plant cells, via the piercing mouthparts of the vector insect: however, these cells generally lack the host enzymes necessary for DNA replication, making it difficult for the virus to replicate. To overcome this block geminiviruses can induce plant cells to reenter the cell cycle from a quiescent state so that viral replication can occur.[11]
Virus Rep protein
The only protein encoded in the viral genome that is essential for geminiviral DNA replication is the geminiviral replication protein Rep.[12] Rep initiates rolling circle replication of the viral DNA and interacts with other host proteins that are components of the replication machinery.
Host RAD54 and DNA polymerases
Host protein
Genus | Host details | Tissue tropism | Entry details | Release details | Replication site | Assembly site | Transmission |
---|---|---|---|---|---|---|---|
Becurtovirus | Spinach | Phloem; sieve; phloem-limited | Viral movement; mechanical inoculation | Budding | Nucleus | Nucleus | Viral movement; contact |
Begomovirus | Dicotyledonous plants | Phloem; sieve; phloem-limited | Viral movement; mechanical inoculation | Budding | Nucleus | Nucleus | Bemisia tabaci whiteflies |
Capulavirus | Dicotyledonous plants | None | Viral movement; mechanical inoculation | Budding | Nucleus | Nucleus | Aphid |
Curtovirus | Dicotyledonous plants | Phloem-limited | Viral movement; mechanical inoculation | Budding | Nucleus | Nucleus | Beet leefhopper |
Eragrovirus | Plants | None | Viral movement; mechanical inoculation | Budding | Nucleus | Nucleus | Treehopper; leafhopper |
Grablovirus | Vitis vinifera (grapevine) | None | Viral movement; mechanical inoculation | Budding | Nucleus | Nucleus | Treehopper |
Mastrevirus | Monocots[15] | None | Viral movement; mechanical inoculation | Budding | Nucleus | Nucleus | Leafhopper |
Topocuvirus | Dicotyledonous plants | None | Cell receptor endocytosis | Budding | Nucleus | Nucleus | Leafhopper |
Turncurtovirus | Turnip | None | Cell receptor endocytosis | Budding | Nucleus | Nucleus | Leafhopper |
Evolution
These viruses may have evolved from a phytoplasma plasmid.[16] Geminiviruses are capable of horizontal gene transfer of genetic information to the plant host.[17]
References
- PMID 28284245.
- ^ a b "Geminiviridae". ICTV Online (10th) Report.
- ^ a b "Virus Taxonomy: 2020 Release". International Committee on Taxonomy of Viruses (ICTV). March 2021. Retrieved 13 May 2021.
- ^ "Viral Zone". ExPASy. Retrieved 15 June 2015.
- PMID 10066833.
- ^ "Genus: Capulavirus - Geminiviridae - ssDNA Viruses - International Committee on Taxonomy of Viruses (ICTV)". International Committee on Taxonomy of Viruses (ICTV). Retrieved 18 August 2017.[dead link]
- ^ "Genus: Grablovirus - Geminiviridae - ssDNA Viruses - International Committee on Taxonomy of Viruses (ICTV)". International Committee on Taxonomy of Viruses (ICTV). Archived from the original on 22 October 2020. Retrieved 18 August 2017.
- ^ Ng TF, Marine R, Wang C, Simmonds P, Kapusinszky B, Bodhidatta L, Oderinde BS, Wommack KE, Delwart E (2012) High variety of known and new RNA and DNA viruses of diverse origins in untreated sewage. J Virol
- PMC 1464598.
- PMID 10698921.
- ^ Hanley Bowdoin lab Archived 11 February 2007 at the Wayback Machine
- ^ Rizvi I, Choudhury NR, Tuteja N. Insights into the functional characteristics of geminivirus rolling-circle replication initiator protein and its interaction with host factors affecting viral DNA replication. Arch Virol. 2015 Feb;160(2):375-87. doi: 10.1007/s00705-014-2297-7. Epub 2014 Dec 2. PMID 25449306
- ^ Kaliappan K, Choudhury NR, Suyal G, Mukherjee SK. A novel role for RAD54: this host protein modulates geminiviral DNA replication. FASEB J. 2012 Mar;26(3):1142-60. doi: 10.1096/fj.11-188508. Epub 2011 Dec 14. PMID 22171001
- ^ Wu M, Wei H, Tan H, Pan S, Liu Q, Bejarano ER, Lozano-Durán R. Plant DNA polymerases α and δ mediate replication of geminiviruses. Nat Commun. 2021 May 13;12(1):2780. doi: 10.1038/s41467-021-23013-2. PMID 33986276; PMCID: PMC8119979
- ^ "Mastrevirus ~ ViralZone".
- PMID 19460138.
- PMID 30546019.