Lactaldehyde reductase (NADPH)
| lactaldehyde reductase (NADPH) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In
enzymology, a lactaldehyde reductase (NADPH) (EC 1.1.1.55) is an enzyme that catalyzes the chemical reaction
- propane-1,2-diol + NADP+ L-lactaldehyde + NADPH + H+
Thus, the two
substrates of this enzyme are 1,2-propanediol and NADP+, whereas its 3 products are L-lactaldehyde, NADPH, and H+
.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is propane-1,2-diol:NADP+ oxidoreductase. Other names in common use include lactaldehyde (reduced nicotinamide adenine dinucleotide phosphate), reductase, NADP+-1,2-propanediol dehydrogenase, propanediol dehydrogenase, 1,2-propanediol:NADP+ oxidoreductase, and lactaldehyde reductase (NADPH).
References
- Gupta NK, Robinson WG (1960). "The enzymatic conversion of lactaldehyde to propanediol". J. Biol. Chem. 235: 1609–12. PMID 13830319.
