Nupapillomavirus
Nupapillomavirus | |
---|---|
Virus classification | |
(unranked): | Virus |
Realm: | Monodnaviria |
Kingdom: | Shotokuvirae |
Phylum: | Cossaviricota |
Class: | Papovaviricetes |
Order: | Zurhausenvirales |
Family: | Papillomaviridae |
Genus: | Nupapillomavirus |
Nupapillomavirus is a genus of
viruses in the family Papillomaviridae.[1] Humans serve as natural hosts. There is only one species in this genus: Nupapillomavirus 1. Diseases associated with this genus include facial warts. This virus has also been detected in some skin carcinomas and premalignant keratoses.[2][3]
Structure
Viruses in Nupapillomavirus are
icosahedral geometries, and T=7 symmetry. The diameter is around 52-55 nm. Genomes are circular, around 8kb in length.[2]
Genus | Structure | Symmetry | Capsid | Genomic arrangement | Genomic segmentation |
---|---|---|---|---|---|
Nupapillomavirus | Icosahedral | T=7 | Non-enveloped | Circular | Monopartite |
Life cycle
Viral replication is nuclear. Entry into the host cell is achieved by attachment of the viral proteins to host receptors, which mediates
dsDNA
bidirectional replication model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear envelope breakdown.
Human serve as the natural host. Transmission routes are contact.[2]
Genus | Host details | Tissue tropism | Entry details | Release details | Replication site | Assembly site | Transmission |
---|---|---|---|---|---|---|---|
Nupapillomavirus | Humans | Epithelial: mucous; epithelial: skin | Cell receptor endocytosis | Lysis | Nucleus | Nucleus | Contact |
References
- PMID 29927370.
- ^ a b c "Viral Zone". ExPASy. Retrieved 15 June 2015.
- ^ "Virus Taxonomy: 2020 Release". International Committee on Taxonomy of Viruses (ICTV). March 2021. Retrieved 10 May 2021.