Oxolinic acid

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Oxolinic acid
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • 5-Ethyl-8-oxo-5,8-dihydro[1,3]dioxolo[4,5-g]quinoline- 7-carboxylic acid
JSmol)
  • CCN1C=C(C(=O)C2=CC3=C(C=C21)OCO3)C(=O)O
  • InChI=1S/C13H11NO5/c1-2-14-5-8(13(16)17)12(15)7-3-10-11(4-9(7)14)19-6-18-10/h3-5H,2,6H2,1H3,(H,16,17) ☒N
  • Key:KYGZCKSPAKDVKC-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Oxolinic acid is a quinolone antibiotic developed in Japan in the 1970s.[1][2] Dosages 12–20 mg/kg orally administered for five to ten days. The antibiotic works by inhibiting the enzyme DNA gyrase. It also acts as a dopamine reuptake inhibitor and has stimulant effects in mice.[3]

See also

References

  1. ^ JP Patent 49138244
  2. PMID 384788
    .
  3. .