Sulfapyridine
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AHFS/Drugs.com | Micromedex Detailed Consumer Information |
MedlinePlus | a682204 |
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JSmol) | |
Melting point | 191 to 193 °C (376 to 379 °F) |
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Sulfapyridine (
History
M&B 693 was one of the first generation of sulfonamide antibiotics. It was discovered by Lionel Whitby at the British firm May & Baker Ltd and logged in their Test Book on 2 November, 1937 under Code No M&B 693.
During the aftermath to the disastrous convoy SC7, in October 1940, Surgeon-Lieutenant John Robertson, RN, of HMS Leith, saved the life of Commodore Lachlan MacKinnon, from the torpedoed Assyrian, who had developed pneumonia, by giving him M&B 693, despite Robertson never having used it before and not knowing the required dosage.[2]
M&B 693 was successfully used to treat Winston Churchill's bacterial pneumonia.[3][4]
The same source records that in 1944 M&B 693 also saved Nero, the Royal Circus lion, from pneumonia.[5]
It could either be taken in tablet form or the powder could be placed in wounds. It was used so widely during the Second World War that May & Baker had difficulty keeping up with demand. It was later largely superseded by penicillin and other sulfonamides.
Related medications
The drug
References
- ^ "Sulfapyride". drugs.com.
- ^ Lund P, Ludlam H (1974). Night of the U-boats. London: New English Library. p. 130.
- S2CID 261386634. Retrieved 7 August 2023.
- ISBN 978-0-19-518775-5. Archived from the original(PDF) on 21 July 2019.
This admirable M&B, from which I did not suffer any inconvenience, was used at the earliest moment; and after a week's fever the intruders were repulsed. I hope all our battles will be equally well conducted....
- ISBN 978-0-19-518775-5. Archived from the original(PDF) on 21 July 2019.
M&B seemed to be everywhere, even at the circus, where the medicine was reported to have pulled Nero, Royal circus lion, through pneumonia, and at the London Zoo, where Winnie the lioness was also treated with M&B 693 for pneumonia.