Pyrinuron
Names | |
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Preferred IUPAC name
N-(4-Nitrophenyl)-N′-[(pyridin-3-yl)methyl]urea | |
Other names
Pyriminil
Vacor | |
Identifiers | |
3D model (
JSmol ) |
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ChemSpider | |
ECHA InfoCard
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100.053.279 |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C13H12N4O3 | |
Molar mass | 272.264 g·mol−1 |
Hazards | |
Occupational safety and health (OHS/OSH): | |
Main hazards
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Toxic |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Pyrinuron (Pyriminil, Vacor) is a
Environmental Protection Agency for use in the United States.[2] If it is ingested by humans in high doses, it may selectively destroy insulin-producing beta cells in the pancreas causing type 1 diabetes.[2] The neurodegeneration associated with Vacor is caused by its conversion to Vacor-mononucleotide (VMN) by NAMPT and VMN's subsequent activation of the NADase SARM1.[3]
References
- PMID 6895844.
- ^ a b "Pyriminil". U.S. National Library of Medicine. Archived from the original on 2013-07-04. Retrieved 2013-11-04.
- .