Endomysium

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Endomysium
Structure of a skeletal muscle. (Endomysium labeled at bottom center.)
Identifiers
TA98A04.0.00.043
TA22007
THH3.03.00.0.00004
FMA9729
Anatomical terminology

The endomysium, meaning within the muscle, is a wispy layer of

muscle connective tissue. This thin layer helps provide an appropriate chemical environment for the exchange of calcium, sodium, and potassium
, which is essential for the excitation and subsequent contraction of a muscle fiber.

Endomysium combines with perimysium and epimysium to create the collagen fibers of tendons, providing the tissue connection between muscles and bones by indirect attachment.[4] It connects with perimysium using intermittent perimysial junction plates.[5]

Collagen is the major protein that composes connective tissues like endomysium.[6] Endomysium has been shown to contain mainly type I and type III collagen components, and type IV and type V in very minor amounts.[7] Others have found type IV and type V more common.[2]

The term cardiac skeleton is sometimes considered synonymous with endomysium in the heart, but cardiac skeleton also refers to the combination of the endomysium and perimysium.

Clinical significance

celiac disease.[8] They do not cause any direct symptoms to muscles, but detection of EMA is useful in the diagnosis of the disease.[9]

See also

References

External links