Estradiol anthranilate
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| Clinical data | |
|---|---|
| Other names | Estradiol 3-anthranilate |
| Routes of administration | By mouth[1][2] |
| Drug class | Estrogen; Estrogen ester |
| Identifiers | |
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JSmol) | |
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Estradiol anthranilate, or estradiol 3-anthranilate, is a
synthetic estrogen and estrogen ester – specifically, the C3 anthranilic acid ester of estradiol – which was described in the late 1980s and was never marketed.[1][2][3][4] In dogs, the oral bioavailability of estradiol anthranilate was found to be 5-fold higher than that of unmodified estradiol.[1][3] However, a subsequent study found that the oral bioavailability of estradiol and estradiol anthranilate did not differ considerably in rats (4.3% and 3.2%, respectively), suggestive of a major species difference.[2][4][5]
See also
References
- ^ S2CID 7308414.
- ^ ISSN 0378-5173.
- ^ ISBN 978-3-642-60107-1.
- ^ ISBN 978-0-387-49785-3.
- ISSN 0378-5173.