Estradiol hemisuccinate

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Not to be confused with Estriol succinate.
Estradiol hemisuccinate
Clinical data
Trade namesEutocol, Hosterona (with progesterone)
Other namesEstradiol succinate; Estradiol 17β-hemisuccinate; Estradiol 17β-succinate
Routes of
administration		By mouth, intramuscular injection
Drug classEstrogen; Estrogen ester
Identifiers
  • 4-{[(17β)-3-Hydroxyestra-1,3,5(10)-trien-17-yl]oxy}-4-oxobutanoic acid
JSmol)
  • C[C@]12CC[C@@H]3c4ccc(cc4CC[C@H]3[C@@H]1CC[C@@H]2OC(=O)CCC(=O)O)O
  • InChI=1S/C22H28O5/c1-22-11-10-16-15-5-3-14(23)12-13(15)2-4-17(16)18(22)6-7-19(22)27-21(26)9-8-20(24)25/h3,5,12,16-19,23H,2,4,6-11H2,1H3,(H,24,25)/t16-,17-,18+,19+,22+/m1/s1
  • Key:YJPIDPAGJSWWBE-FNIAAEIWSA-N

Estradiol hemisuccinate (brand name Eutocol), or simply estradiol succinate, also known as estradiol 17β-hemisuccinate, is an estrogen medication and an estrogen ester – specifically, the hemisuccinate ester of estradiol.[1] It is used as a component of hormone replacement therapy for menopause.[2] Like other estrogens, estradiol hemisuccinate has been found to have beneficial effects on the skin, with improvement of skin thickness observed.[2][3]

Estradiol hemisuccinate is also a component of

withdrawal bleeding in women with amenorrhea.[4][5][6]

See also

References

  1. ISBN 978-1-4757-2085-3
    .
  2. ^
    ISBN 978-3-540-89655-5
    .
  3. PMID 8116726
    .
  4. ^ "¿Qué es Hosterona y para qué sirve?" [What is Hosterona and what is it for?]. matchmyrx.com (in Spanish). PRX Control Solutions. Archived from the original on 13 April 2019.
  5. ^ "Hosterona - Para qué sirve" [Hosterona - What it is for]. Los Medicamentos (in Spanish). 23 November 2012.
  6. ^ "HOSTERONA (Hormonoterapia)". Laboratorio GADOR.
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