Estradiol dibutyrate

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Estradiol dibutyrate
JSmol)
  • O(C(CCC)=O)[C@]1CC[C@]([H])2[C@@]([H])3CCC4C=C(C=CC=4[C@@]3([H])CC[C@@]21C)OC(=O)CCC
  • InChI=1S/C26H35O4/c1-4-6-24(27)29-18-9-11-19-17(16-18)8-10-21-20(19)14-15-26(3)22(21)12-13-23(26)30-25(28)7-5-2/h9,11,16,20-22H,4-8,10,12-15H2,1-3H3/t20-,21-,22+,26+/m1/s1
  • Key:YQLMZRSLVHCBEL-CQAGSAPUSA-N

Estradiol dibutyrate (EDBu), or estradiol dibutanoate, is an

formulation of estradiol dibutyrate, testosterone caproate, and hydroxyprogesterone heptanoate which was developed in the 1950s.[2]

See also

References

  1. PMID 13689684
    .
  2. ^ a b Ermiglia G, Valli P (1957). "Triormon depositum in climacteric syndrome. Curves of excretion of catabolites and duration of the therapeutic effect". Quaderni Clin. Ostet. E Ginecol. 12: 284–93. Triormon depositum (estradiol dibutyrate 3, testosterone caprylate 50, and hydroxyprogesterone heptanoate 30 mg.), administered in castor oil-benzyl benzoate soln. or polyvinylpyrrolidone suspension to 21 women in climacteric, was followed by estradiol, pregnanediol, and 17-keto steroid urinary curves, most with a peak at the 4th day, and approaching starting values at the 8-10th day. The therapeutic efficacy of the drug was satisfactory.
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