Haloprogin

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"Polik" redirects here. For other uses, see Polik (disambiguation).
Haloprogin
Clinical data
Routes of
administration		Topical
ATC code
Legal status
Legal status
  • US: Not available
Identifiers
  • 1,2,4-Trichloro-5-[(3-iodoprop-2-yn-1-yl)oxy]benzene
JSmol)
Melting point113.5 °C (236.3 °F)
Solubility in waterInsoluble mg/mL (20 °C)
  • Clc1cc(OCC#CI)c(Cl)cc1Cl
  • InChI=1S/C9H4Cl3IO/c10-6-4-8(12)9(5-7(6)11)14-3-1-2-13/h4-5H,3H2 checkY
  • Key:CTETYYAZBPJBHE-UHFFFAOYSA-N checkY
  (verify)

Haloprogin is an

antifungal drug used to treat athlete's foot and other fungal infections.[1]
It is marketed in creams under the trade names Halotex, Mycanden, Mycilan, and Polik.

Action

Haloprogin was previously used in 1% topical creams as an antifungal agent. It was marketed

tinea infections of the skin. The mechanism of action is unknown.[2]

Haloprogin had a high incidence of side effects including: irritation, burning, vesiculation (blisters), scaling, and itching. It has since been discontinued due to the emergence of more modern antifungals with fewer side effects.[3]

References

  1. S2CID 71471801
    .
  2. ^ "Haloprogin". Drugs@FDA. Food and Drug Administration. Retrieved 2007-02-17.
  3. ^ "Haloprogin". DrugBank. University of Alberta. Nov 6, 2006. Retrieved 2007-02-17.
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