Flutrimazole

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Flutrimazole
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • (RS)-1-[(2-Fluorophenyl)(4-fluorophenyl)benzyl]-1H-imidazole
JSmol)
ChiralityRacemic mixture
  • Fc1ccc(cc1)C(c2c(F)cccc2)(c3ccccc3)n4ccnc4
  • InChI=1S/C22H16F2N2/c23-19-12-10-18(11-13-19)22(26-15-14-25-16-26,17-6-2-1-3-7-17)20-8-4-5-9-21(20)24/h1-16H checkY
  • Key:QHMWCHQXCUNUAK-UHFFFAOYSA-N checkY
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Flutrimazole is a wide-spectrum

mycoses of the skin. Flutrimazole is an imidazole derivative. Its antifungal activity has been demonstrated in in vivo and in vitro studies to be comparable to that of clotrimazole and higher than bifonazole.[1]

Mechanism of action

It interferes with the synthesis of ergosterol by inhibiting the activity of the enzyme lanosterol 14 α-demethylase.[citation needed]

See also

References

The Merck Index, 12th Edition. 4247