Immune receptor
An immune receptor (or immunologic receptor) is a receptor, usually on a cell membrane, which binds to a ligand (usually another protein, such as cytokine) and causes a response in the immune system.
Types
The main receptors in the
T cell receptors.[1]
| Receptor | Bind to [1] | Function[1] |
|---|---|---|
| ) | Pathogen-associated molecular patterns (PAMP) | Mediate cytokine production → inflammation → destroying pathogen |
killer inhibitor receptors (KARs and KIRs)
|
Avails NK cells to identify abnormal host cells (KAR) or inhibit inappropriate host cell destruction (KIR)
| |
| Complement receptors | Complement proteins on e.g. microbes |
Allow phagocytic and B cells to recognize microbes and immune complexes |
Fc receptors
|
Epitope-antibody complexes | Stimulate phagocytosis |
B cell receptors
|
Epitopes | B cell differentiation into plasma cells and proliferation |
T cell receptors
|
Linear epitopes bound to MHC | Activate T cells |
| Cytokine receptors | Cytokines | Regulation and co-ordination of immune responses |
See also
References
- ^ ISBN 978-0-7817-9543-2. Page 20
External links
- Immunologic + receptor at the U.S. National Library of Medicine Medical Subject Headings (MeSH)