mir-3180 microRNA precursor family
| mir-3180 | |
|---|---|
 Conserved secondary structure of the mir-3180 miRNA. | |
| Identifiers | |
| Symbol | mir-3180 |
| Rfam | RF02010 |
| miRBase family | MIPF0000894 |
| HGNC | 38382 |
| Other data | |
| RNA type | microRNA |
| Domain(s) | Eukaryota; Metazoa |
| PDB structures | PDBe |
In
Homo sapiens
.
Species distribution
The presence of mir-3180 has been detected in a range of
In some of these species the presence of mir-3180 has been shown experimentally, in others the genes encoding mir-3180 might have been predicted computationally.Genomic location
The mir-3180
humans
there are five mir-3180 clusters, these contain five genes encoding miRNAs (mir-3180-1, mir-3180-2, mir-3180-3, mir-3180-4 and mir-3180-5). The mir-3180 genes have the following locations:
hsa-mir-3180-1 chr16 Start: 14911220 End: 14911313 Strand: +
hsa-mir-3180-2 chr16 Start: 16309879 End: 16309966 Strand: +
hsa-mir-3180-3 chr16 Start: 18402178 End: 18402271 Strand: -
hsa-mir-3180-4 chr16 Start: 15154850 End: 15155002 Strand: -
hsa-mir-3180-5 chr16 Start: 2135977 End: 2136129 Strand: -
Association with cancer
Recently there has been much interest in abnormal levels of expression of microRNAs in cancers. Upregulation of mir-3180 has been found in cancers. Increased levels of mir-3180 have been found in colon cancer.[6]
See also
Further reading
External links
 | This genetics article is a stub. You can help Wikipedia by expanding it. |