mir-BHRF1-3 microRNA precursor family
| mir-BHRF1-3 microRNA precursor family | |
|---|---|
| SO | SO:0001244 |
| PDB structures | PDBe |
The mir-BHRF1-3 microRNA precursor found in Human herpesvirus 4 (Epstein–Barr virus).[1] In Epstein-Barr virus, mir-BHRF1-3 is found in the 3' UTR of the BHRF1 (Bam HI fragment H rightward open reading frame 1) gene, which is known to encode a distant Bcl-2 homolog. The mature sequence is excised from the 5' arm of the hairpin.[2] Two other miRNA precursors were found in this reading frame, namely Mir-BHRF1-1 and Mir-BHRF1-2.[2]
BHRF-1-3 miRNA is thought to operate as part of a 'miRNA cluster' with two other microRNAs also found in the Epstein–Barr virus genome.[3] BHRF-3 has been shown to be expressed in latency-III infected lymphoblasts.[4]
References
External links
 | This molecular or cell biology article is a stub. You can help Wikipedia by expanding it. |