miR-296
miR-296 | |
---|---|
Chr. 20 q13.32 | |
PDB structures | PDBe |
miR-296 is a family of microRNA precursors found in mammals, including humans. The ~22 nucleotide mature miRNA sequence is excised from the precursor hairpin by the enzyme Dicer.[1] This sequence then associates with RISC which effects RNA interference.[2]
miR-296 has been named an "angiomiR"
miR-296 has predicted target sites in the transcription factor NANOG[7] and may also contribute to carcinogenesis by dysregulating p53.[8]
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