3-Methoxytyramine

3-Methoxytyramine

Names
Preferred IUPAC name 4-(2-Aminoethyl)-2-methoxyphenol
Other names 3-O-Methyldopamine
Identifiers
CAS Number	554-52-9 Y
3D model ( JSmol )	Interactive image
ChEBI	CHEBI:1582
ChemSpider	1606 N
ECHA InfoCard	100.122.789
IUPHAR/BPS	6642
MeSH	3-methoxytyramine
PubChem CID	1669
UNII	JCH2767EDP Y
CompTox Dashboard (EPA)	DTXSID40862189
InChI InChI=1S/C9H13NO2/c1-12-9-6-7(4-5-10)2-3-8(9)11/h2-3,6,11H,4-5,10H2,1H3 N Key: DIVQKHQLANKJQO-UHFFFAOYSA-N N InChI=1/C9H13NO2/c1-12-9-6-7(4-5-10)2-3-8(9)11/h2-3,6,11H,4-5,10H2,1H3 Key: DIVQKHQLANKJQO-UHFFFAOYAB
SMILES COc1cc(ccc1O)CCN
Properties
Chemical formula	C9H13NO2
Molar mass	167.21 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

3-Methoxytyramine (3-MT), also known as 3-methoxy-4-hydroxyphenethylamine, is a human

Originally thought to be physiologically inactive, 3-MT has recently been shown to act as an agonist of human TAAR1.^[1][2]

Occurrence

3-Methoxytyramine occurs naturally in the

In humans, 3-methoxytyramine is a trace amine that occurs as a metabolite of dopamine.^[1]

Biosynthetic pathways for catecholamines and trace amines in the human brain[6][7][8] L-Phenylalanine L-Tyrosine L-DOPA Epinephrine Phenethylamine p-Tyramine Dopamine Norepinephrine N-Methylphenethylamine N-Methyltyramine p-Octopamine Synephrine 3-Methoxytyramine AADC AADC AADC primary pathway PNMT PNMT PNMT PNMT AAAH AAAH brain CYP2D6 minor pathway COMT DBH DBH In humans, catecholamines and phenethylaminergic trace amines are derived from the amino acid L-phenylalanine.

See also

• Tyramine
• 3,4-Dimethoxyphenethylamine

References