N-Acetylputrescine

N-Acetylputrescine
Names
	IUPAC name N-(4-aminobutyl)acetamide
	Other names Acetylputrescine; Monoacetylputrescine; NacPut
Identifiers
CAS Number	5699-41-2;
3D model ( JSmol)	Interactive image;
ChEBI	CHEBI:17768;
ChEMBL	ChEMBL81241;
ChemSpider	109095;
ECHA InfoCard	100.219.140
EC Number	691-457-0;
KEGG	C02714;
PubChem CID	122356;
UNII	8FTM5ZL5A6;
CompTox Dashboard (EPA)	DTXSID80205596 ;
	InChI InChI=1S/C6H14N2O/c1-6(9)8-5-3-2-4-7/h2-5,7H2,1H3,(H,8,9) Key: KLZGKIDSEJWEDW-UHFFFAOYSA-N;
	SMILES CC(=O)NCCCCN;
Properties
Chemical formula	C6H14N2O
Molar mass	130.19 g/mol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

N-Acetylputrescine (NacPut), also known as monoacetylputrescine, is an

γ-aminobutyric acid (GABA) from putrescine.^[1]^[2]^[3]

The

γ-aminobutyraldehyde (GABAL or GABA aldehyde) as an intermediate instead.^[1] It has been estimated that about 2 to 3% of GABA is synthesized from putrescine in the mouse brain, whereas in the case of the rat brain, the amount was negligible.^[1]

In 2021, it was discovered that MAO-B does not mediate

MAO-B inhibitors in the treatment of Parkinson's disease.^[4]^[3]

References

^
PMID 11837891
.

^
PMID 15221502
.

^
PMID 34244591
.

^
PMID 35457272
.

[WatanabeMaemuraKanbara2002-1] 
PMID 11837891
.

[Seiler2004-2] 
PMID 15221502
.

[ChoKimSim2021-3] 
PMID 34244591
.

[NamSaJu2022-4] 
PMID 35457272
.

[1]

[2]

[3]

[4]