Ceftiofur

Source: Wikipedia, the free encyclopedia.

Ceftiofur
QJ51DD90 (WHO)
Legal status
Legal status
Identifiers
  • (6R,7R)-7-[ [(2Z)-2-(2-Amino-1,3-thiazol-4-yl)- 2-methoxyiminoacetyl]amino]-3-(furan-2- carbonylsulfanylmethyl)-8-oxo-5-thia-1- azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
JSmol)
  • O=C2N1/C(=C(\CS[C@@H]1[C@@H]2NC(=O)C(=N\OC)/c3nc(sc3)N)CSC(=O)c4occc4)C(=O)O
  • InChI=1S/C19H17N5O7S3/c1-30-23-11(9-7-34-19(20)21-9)14(25)22-12-15(26)24-13(17(27)28)8(5-32-16(12)24)6-33-18(29)10-3-2-4-31-10/h2-4,7,12,16H,5-6H2,1H3,(H2,20,21)(H,22,25)(H,27,28)/b23-11-/t12-,16-/m1/s1 checkY
  • Key:ZBHXIWJRIFEVQY-IHMPYVIRSA-N checkY
  (verify)

Ceftiofur is an

pharmaceutical company Zoetis as Excenel,[3] Naxcel, and Excede and is also the active ingredient in that company's Spectramast LC (lactating cow formulation) and Spectramast DC (dry cow formulation) product.[citation needed
]

It is resistant to the

E. coli strains resistant to ceftiofur have been reported.[4]

The metabolite desfuroylceftiofur also has antibiotic activity.[5] The two compounds are measured together to measure for antibiotic activity in milk (alongside other antibiotics).[6]

References

  1. ^ "Naxcel EPAR". European Medicines Agency. 20 October 2009. Retrieved 29 June 2024.
  2. PMID 3631686
    .
  3. ^ "Pfizer Animal Health Dairy Information on Products and Solutions". Archived from the original on 13 October 2007. Retrieved 20 November 2007.
  4. PMID 16751500
    .
  5. PMID 8844576
    .
  6. ^ "BetaStar Plus / For beta-lactam antibiotics / Product information sheet" (PDF). Neogen. Retrieved 9 September 2014.


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