Tazobactam

Source: Wikipedia, the free encyclopedia.
Not to be confused with Teixobactin.
Tazobactam
Clinical data
AHFS/Drugs.comInternational Drug Names
License data
Pregnancy
category
  • B
Routes of
administration		Intravenous
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • (2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide
JSmol)
  • O=S2(=O)[C@]([C@@H](N1C(=O)C[C@H]12)C(=O)O)(Cn3nncc3)C
  • InChI=1S/C10H12N4O5S/c1-10(5-13-3-2-11-12-13)8(9(16)17)14-6(15)4-7(14)20(10,18)19/h2-3,7-8H,4-5H2,1H3,(H,16,17)/t7-,8+,10+/m1/s1 checkY
  • Key:LPQZKKCYTLCDGQ-WEDXCCLWSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Tazobactam is a

inhibits the action of bacterial β-lactamases, especially those belonging to the SHV-1 and TEM groups. It is commonly used as its sodium salt
, tazobactam sodium.

Tazobactam is combined with the

β-lactamase and would normally degrade piperacillin.[1]

Tazobactam was patented in 1982 and came into medical use in 1992.[2]

See also

References

  1. PMID 10511459
    .
  2. ISBN 9783527607495
    .
Stub icon

This systemic antibiotic-related article is a stub. You can help Wikipedia by expanding it.

Retrieved from "https://en.wikipedia.org/w/index.php?title=Tazobactam&oldid=1170404141"