Circumvallate placenta

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Circumvallate Placenta
The thickened ring of membranes on the fetal surface of a circumvallate placenta, making it appear as though the central part of the placenta has been exposed.
SpecialtyObstetrics Edit this on Wikidata

Circumvallate placenta is a rare condition affecting about 1-2% of pregnancies, in which the amnion and chorion fetal membranes essentially "double back" on the fetal side around the edges of the placenta.[1] After delivery, a circumvallate placenta has a thick ring of membranes on its fetal surface.[2] Circumvallate placenta is a placental morphological abnormality associated with increased fetal morbidity and mortality due to the restricted availability of nutrients and oxygen to the developing fetus.

frequent fetal monitoring and, if necessary, emergency cesarean section.[1]

In a circumvallate placenta, the chorionic plate, which forms the fetal surface of the placenta, tends to be smaller than the basal plate, which forms the maternal surface of the placenta. This results in the elevation of the placental margin and the appearance of an annular shape.[3] The fetal surface is divided into a central depressed zone surrounded by a thickened white ring which is incomplete. The ring is situated at varying distances from the margin, or edges, of the placenta. This thick ring of membranes is composed of a double fold of amnion and chorion with degenerated decidua vera and fibrin in between. Blood vessels, supplying nutrients and carrying waste products to and from the developing fetus, radiate from the umbilical cord insertion to as far as the ring of membranes, and then disappears from view.[4]

Signs & Symptoms

A circumvallate placenta does not always induce associated

symptomatic mothers, physicians may be able to detect a circumvallate placenta based on the presentation of the following signs.[1]

Complications

Circumvallate placenta has also been associated with a higher incidence of

fetal abnormalities
.

Cause

Unfortunately, there is no known cause of circumvallate placenta and no major

uterine wall, although these potential causes are still not well-understood in terms of their relation to circumvallate placenta.[4]

Risk factors

Hypertensive disorders

Women entering a

anti-hypertensive medications during pregnancy and are advised to monitor their blood pressure throughout the course of pregnancy.[5]

Maternal age

Another

pregnancy complications in mothers who are age 35 or older at time of pregnancy.[6]

Substance use

Further, yet another factor inducing

Women with these risk factors are recommended additional surveillance during pregnancy to monitor fetal development and to be able to detect fetal, placental, or umbilical cord abnormalities as early as possible.

Pathophysiology/Mechanism

The

pregnancy complications, birth defects, and/or death of the fetus
.

In a normal placenta, there is a smooth transition from the parenchymal villous chorion to the membranous chorion at the border of the placental plate. Fetal blood vessels subdivide from the umbilical cord and spread diagonally throughout the parenchyma towards the edge of the placental plate.[4]

In a circumvallate placenta, the

hemorrhage, or fibrin depositing. This results in the reduction in size of the chorionic plate of the placenta, further causing the membranes on the fetal side to fold backward on themselves.[medical citation needed] The parenchymal villous chorion continues to proliferate beyond the tethered membranes and appears to protrude outward. The fetal blood vessels are directed downward and then horizontally in order to provide blood flow to the most peripheral parts of the placental plate extending beyond the tethered membranes.[4]

Since a portion of the

Premature rupture of membranes often occurs as a result of infection in the uterus, which can be caused by the occurrence vaginal bleeding
. Therefore, placental abnormalities such as circumvallate placenta can be extremely detrimental in causing the onset of associated conditions.

Diagnosis

In some cases, a

routine ultrasound screenings. In most cases, a circumvallate placenta is not discovered until physical examination of the placenta after delivery of the fetus.[1] For this reason, circumvallate placenta is very difficult to diagnose during pregnancy
.

On

screening purposes
.

Complete circumvallate placenta involves morphological abnormality of the entire dimension of the

clinically significant as complete circumvallate placenta.[4]

The accurate diagnosis of circumvallate placenta during

sonography to accurately diagnosis circumvallate placenta during pregnancy is quite limited, research studies
continue to emerge at the possibility of doing so.

Treatment/Management

Although there is no

C-section being more favorable compared to vaginal delivery.[1]

In women experiencing a

severe blood loss
.

If oligohydramnios occurs as a result of a circumvallate placenta, a treatment called amnioinfusion may be considered to replenish the amount of lost amniotic fluid within the amniotic sac. Amnioinfusion may help in preventing underdevelopment of the lungs.

If diagnosed with a circumvallate placenta, consistent

cesarean section will most likely be suggested by a physician.[3]

Prognosis

Unfortunately, there is currently not a

complications.[1] In other cases, patients diagnosed with circumvallate placenta are able to carry their babies until term or near-term
.

Epidemiology

Circumvallate placenta is a very rare condition affecting pregnant women. This condition is a placental morphological abnormality, with the placenta being formed during the early periods of pregnancy. Women are able to become pregnant with the onset of ovulation and menstruation in early adolescence, with most women becoming pregnant during adulthood. Circumvallate placenta is currently known to affect about 1-2% of pregnancies. It is not virally transmissible to other individuals, nor can it be transferred through contact or respiration.[1]

There are no specific

pregnancy complications like circumvallate placenta if quality prenatal care
is not available.

Women with

Research

The

.

A

required oxygen and nutrition through the placenta, and this can further cause other severe complications
.

In the study, a 22-year-old woman at

vaginal bleeding during the current pregnancy.[3]

Upon presenting for

fetal heart rate every 25 minutes without contractions. Fetal motion was present, with the placenta appearing enlarged and spherical.[3]

Decreases in the

newborn was discharged from the neonatal intensive care unit 105 days post-birth.[3]

This case study discussed the association of circumvallate placenta and abnormal

In a separate

loss of fetal life
.

Thus, it is highly recommended that if

requent follow-ups using ultrasonography to monitor fetal developmental and placental and umbilical cord structure and function.[8]

pregnancy complications in high-risk pregnancies. Circumvallate placenta appears to be correlated with reduced placental efficacy due to increased placental thickness and abnormal villi function, affecting the Sflt/PlGF ratio. It is thought that obtaining Sflt/PlGF ratios can be used to determine deficiencies in placental function in cases of placental abnormalities.[3] Future research analyzing the contribution of biomarkers like Sflt/PlGF to predict placental abnormalities would be influential to our understanding of many placental deformities, including circumvallate placenta.[3]

Due to the rare occurrences of circumvallate placenta, more extensive research trials are unavailable, resulting in data limitations. Therefore, the clinical importance of circumvallate placenta remains uncertain.[3]

References

  1. ^ a b c d e f g h i j k l m n "Circumvallate placenta: Risks, causes, and treatment". www.medicalnewstoday.com. 2020-03-09. Retrieved 2022-11-07.
  2. PMID 9518951
    .
  3. ^ .
  4. ^ .
  5. ^ a b c d e National Academies of Sciences, Engineering; Division, Health and Medicine; Education, Division of Behavioral and Social Sciences and; Board on Children, Youth; Settings, Committee on Assessing Health Outcomes by Birth; Backes, Emily P.; Scrimshaw, Susan C. (2020-02-06). Epidemiology of Clinical Risks in Pregnancy and Childbirth. National Academies Press (US).
  6. PMID 21957193
    .
  7. ^ updated, Dr Lewis Potter·Data Interpretation·Last (2011-03-29). "How to Read a CTG | CTG Interpretation | Geeky Medics". Retrieved 2022-12-13.
  8. ^
    PMID 29201670
    .

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