Domoprednate

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Domoprednate
Clinical data
Trade namesStermonid
Other namesRo 12-7024; 11β-Hydroxy-D-homopregna-1,4-diene-3,20-dione 17α-butyrate
Routes of
administration		Topical
Drug classCorticosteroid; Glucocorticoid
Identifiers
  • [(1R,4aS,4bS,10aR,10bS,11S,12aS)-1-Acetyl-11-hydroxy-10a,12a-dimethyl-8-oxo-2,3,4,4a,4b,5,6,10b,11,12-decahydrochrysen-1-yl] butanoate
JSmol)
  • CCCC(=O)O[C@@]1(CCC[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2CCC4=CC(=O)C=C[C@]34C)O)C)C(=O)C
  • InChI=1S/C26H36O5/c1-5-7-22(30)31-26(16(2)27)12-6-8-20-19-10-9-17-14-18(28)11-13-24(17,3)23(19)21(29)15-25(20,26)4/h11,13-14,19-21,23,29H,5-10,12,15H2,1-4H3/t19-,20-,21-,23+,24-,25-,26-/m0/s1
  • Key:IYBYNRHXGXDDDS-VRRJBYJJSA-N

Domoprednate (brand name Stermonid; developmental code name Ro 12-7024) is a

synthetic glucocorticoid corticosteroid which was developed in the late 1970s and 1980s.[1][2][3][4][5]

References

  1. ISBN 978-1-4757-2085-3
    .
  2. PMID 6370748
    .
  3. PMID 3888708
    .
  4. PMID 3888709
    .
  5. PMID 3653463
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