N-acetylphosphatidylethanolamine-hydrolysing phospholipase D
| N-acetylphosphatidylethanolamine-hydrolysing phospholipase D | |||||||||
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| Identifiers | |||||||||
ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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N-acetylphosphatidylethanolamine-hydrolysing phospholipase D (EC 3.1.4.54, NAPE-PLD, anandamide-generating phospholipase D, N-acyl phosphatidylethanolamine phospholipase D, NAPE-hydrolyzing phospholipase D) is an enzyme with systematic name 'N-acetylphosphatidylethanolamine phosphatidohydrolase.[1][2] It catalyses the following chemical reaction
- N-acylphosphatidylethanolamine + H2O N-acylethanolamine+ a 1,2-diacylglycerol 3-phosphate
This enzyme is involved in the biosynthesis of anandamide.
See also
References
- Magotti, Paola; Bauer, Inga; Igarashi, Miki; Babagoli, Masih; Marotta, Roberto; Piomelli, Daniele; Garau, Gianpiero (March 2015). "Structure of Human N-Acylphosphatidylethanolamine-Hydrolyzing Phospholipase D: Regulation of Fatty Acid Ethanolamide Biosynthesis by Bile Acids". Structure. 23 (3): 598–604. PMID 25684574.
External links
- N-acetylphosphatidylethanolamine-hydrolysing+phospholipase+D at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
- N-acyl phosphatidylethanolamine phospholipase D (NAPEPLD ((C7orf18, FMP30, NAPE-PLD)) Human Protein Atlas
