Norgesterone

Source: Wikipedia, the free encyclopedia.
Norgesterone
Progestin
ATC code
  • None
Identifiers
  • (8R,9S,13S,14S,17R)-17-ethenyl-17-hydroxy-13-methyl-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
JSmol)
  • CC12CCC3C(C1CCC2(C=C)O)CCC4=C3CCC(=O)C4
  • InChI=1S/C20H28O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h3,16-18,22H,1,4-12H2,2H3/t16-,17-,18+,19+,20+/m1/s1
  • Key:YPVUHOBTCWJYNQ-SLHNCBLASA-N

Norgesterone, also known as norvinodrel or vinylestrenolone and sold under the brand name Vestalin, is a

birth control pills for women but is now no longer marketed.[1][2][3][4] It was used in combination with the estrogen ethinylestradiol.[2][3][4] It is taken by mouth.[5][6]

Norgesterone is a progestin, or a

synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone.[7] It has no androgenic activity.[7]

Norgesterone was first described in 1962.[8][9] It is no longer available.[10]

Medical uses

Norgesterone was used in combination with

birth control pills to prevent pregnancy.[2] It is no longer available.[10]

Pharmacology

Pharmacodynamics

Norgesterone is a

Chemistry

Norgesterone, also known as 17α-vinyl-δ5(10)-19-nortestosterone or as 17α-vinylestr-5(10)-en-17β-ol-3-one, is a

19-nortestosterone.[1] Analogues of norgesterone include norvinisterone (17α-vinyl-19-nortestosterone) and vinyltestosterone (17α-vinyltestosterone).[1]

History

Norgesterone was first described in 1962.[8][9]

Society and culture

Generic names

Norgesterone is the

INNTooltip International Nonproprietary Name.[1] It has also been referred to as norvinodrel, vinylestrenolone, and vinylnoretynodrel.[1][11]

Brand names

Norgesterone was marketed in combination with

birth control pill under the brand name Vestalin.[2][3][4]

Availability

Norgesterone is no longer marketed and hence is no longer available in any country.[10]

References