Phenindamine
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Phenindamine (Nolahist, Thephorin) is an
allergies, such as sneezing, itching, rashes, and hives. Its efficacy against some symptoms of opioid withdrawal was researched in the 1950s and 1960s in a number of countries; William S. Burroughs' book Junkie
mentions this technique. Like many other first-generation antihistamines, phenindamine has useful potentiating effects on many narcotic analgesics and is even more useful with those opioids which release histamine when in the body.
Nolahist was originally manufactured in the US by Carnrick Laboratories, and later by Amarin Pharmaceuticals. When that company ceased its American operations, its product line was acquired by
Valeant
, but they declined to resume manufacturing Nolahist. The last produced lot bore an expiration date of 10/2005, and the product is no longer available.
Phenindamine does exhibit
alphaprodine to cyproheptadine to certain herbicides and other industrial chemicals; the.[2] In the example at hand, the compound isophenidamine (60295-96-7 MSDS), which is inactive.[2]
See also
References
- ^ US 2546652, Plati JT , Wenner W, "Pyridindenes and process for their manufacture", assigned to F Hoffmann La Roche AG
- ^ PMID 7381716.