Bamipine

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Bamipine
Clinical data
Trade namesSoventol
AHFS/Drugs.comInternational Drug Names
Routes of
administration		Oral?, topical
ATC code
Identifiers
  • N-benzyl-1-methyl-N-phenyl-piperidin-4-amine
JSmol)
  • N(c1ccccc1)(Cc2ccccc2)C3CCN(C)CC3
  • InChI=1S/C19H24N2/c1-20-14-12-19(13-15-20)21(18-10-6-3-7-11-18)16-17-8-4-2-5-9-17/h2-11,19H,12-16H2,1H3 checkY
  • Key:VZSXTYKGYWISGQ-UHFFFAOYSA-N checkY
  (verify)

Bamipine (trade name Soventol)

H1 antihistamine with anticholinergic properties.[2] It is used as an antipruritic ointment.[3] No oral use is known.[4]

Adverse effects

Side effects are typical of an old (first-generation) antihistamine: tiredness in adults, agitation in children,

eczema can be worsened by bamipine ointment.[5]

Contraindications and interactions

No clinically relevant contraindications or interactions with other drugs are known.[5]

Pharmacology

Pharmacokinetics

When applied topically, the maximal effect is reached after 20 to 60 minutes and lasts up to 48 hours. Bamipine is not absorbed through intact skin in relevant doses.[5]

References

  1. ISBN 978-0-8155-1856-3
    .
  2. ISBN 978-0-12-813428-3.{{cite book}}: CS1 maint: location missing publisher (link
    )
  3. ^ WO 0236163, Pairet M, Pieper MP, Meade CJ, Schmelzer C, "Pharmaceutical compositions containing tiotropium salts and antihistamines and their use", published 10 May 2002, assigned to Boehringer Ingelheim 
  4. ^ International Drug Names: Bamipine.
  5. ^ a b c Haberfeld H, ed. (2015). Austria-Codex (in German). Vienna: Österreichischer Apothekerverlag. Soventol-Gel.