Buclizine

Source: Wikipedia, the free encyclopedia.
Buclizine
Clinical data
AHFS/Drugs.comMicromedex Detailed Consumer Information
ATC code
Identifiers
  • (RS)-1-[(4-chlorophenyl)- phenyl-methyl]-4- [(4-tert-butylphenyl) methyl] piperazine
JSmol)
ChiralityRacemic mixture
  • Clc1ccc(cc1)C(c2ccccc2)N3CCN(CC3)Cc4ccc(cc4)C(C)(C)C
  • InChI=1S/C28H33ClN2/c1-28(2,3)25-13-9-22(10-14-25)21-30-17-19-31(20-18-30)27(23-7-5-4-6-8-23)24-11-15-26(29)16-12-24/h4-16,27H,17-21H2,1-3H3 checkY
  • Key:MOYGZHXDRJNJEP-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Buclizine is an antihistamine and anticholinergic of the diphenylmethylpiperazine group. It is considered to be an antiemetic, similar to meclizine.[1]

In the

McNeil Healthcare for migraines.[2]

References

  1. PMID 22469258
    .
  2. PMID 4070325
    .
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