Small nucleolar RNA SNORD35
Small nucleolar RNA SNORD35 | |
---|---|
SO | SO:0000593 |
PDB structures | PDBe |
In
small nucleolar RNA
(snoRNA) and also often referred to as a guide RNA.
snoRNA U35 belongs to the
C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.[1]
U35 is encoded in intron 6 of ribosomal protein L13A and intron 3 of ribosomal protein S11 in humans[2] and at homologous positions in mouse and chicken ribosomal protein genes. U35 is predicted to guide the 2'O-ribose methylation of 28S ribosomal RNA (rRNA) residue C4506.[2][3]
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