Small nucleolar RNA R66

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Small nucleolar RNA R66
GO
GO:0006396 GO:0005730
SOSO:0000593
PDB structuresPDBe

In

small nucleolar RNA
(snoRNA) and also often referred to as a guide RNA.

snoR66 belongs to the

C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.[1]

snoR66 was identified by a computational screening of the rice Oryza sativa genome and is proposed to acts as a methylation guide for 18S ribosomal RNA in plants.[2] Rice snoR66 has also been alternatively named snoZ269. Its should also not be confused with the snoRNA identified in yeast (Saccharomyces cerevisiae) and called snR66.[3]

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