Small nucleolar RNA TBR17

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Small nucleolar RNA TBR17
GO
GO:0006396 GO:0005730
SOSO:0000593
PDB structuresPDBe

In

small nucleolar RNA
(snoRNA) and also often referred to as a guide RNA.

snoRNA TBR17 belongs to the

C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.[1]

TBR17 was one of seventeen snoRNAs identified in Trypanosoma brucei by immunoprecipitation with anti-fibrillarin antibodies.[2] Together with TBR5 and TBR7 it is a part of a tandemly repeated snoRNA gene cluster, located within the spliced leader RNA (SLA).[3] The cluster genes are produced as polycistronic RNAs.[4]

See also

References

External links