Small nucleolar RNA SNORD65
Small nucleolar RNA SNORD65 | |
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SO | SO:0000593 |
PDB structures | PDBe |
In
C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.[1]
SNORD65 is the human orthologue of the mouse MBII-135 snoRNA[2] and is predicted to guide 2'O-ribose methylation of the small subunit (SSU) ribosomal RNA (rRNA), 18S, on position U627.[3]
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