Small nucleolar RNA SNORA77

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Small nucleolar RNA SNORA77
GO
GO:0006396 GO:0005730
SOSO:0000594
PDB structuresPDBe

In

small nucleolar RNA
(snoRNA).

SNORA77 was identified by computational screening and its expression in mouse experimentally verified by Northern blot and primer extension analysis.[1] It belongs to the

H/ACA box class of snoRNAs as it has the predicted hairpin-hinge-hairpin-tail structure and conserved H/ACA-box motifs.[2]

SNORA77 is proposed to guide the pseudouridylation of 18S ribosomal RNA (rRNA) residue U814.[3] Pseudouridylation is the

isomerisation of the nucleoside uridine to the different isomeric form pseudouridine
.

References

External links