Small nucleolar RNA TBR7
| Small nucleolar RNA TBR7 | |
|---|---|
| SO | SO:0000593 |
| PDB structures | PDBe |
In
small nucleolar RNA
(snoRNA) and also often referred to as a guide RNA.
snoRNA TBR7 belongs to the
C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.[1]
TBR7 was one of seventeen snoRNAs identified in Trypanosoma brucei by immunoprecipitation with anti-fibrillarin antibodies.[2] It is predicted to guide the 2'O ribosome methylation of 18s ribosomal RNA (rRNA).
Together with TBR5 and TBR17 it is a part of a tandemly repeated snoRNA gene cluster, located within the spliced leader RNA (SLA).[3] The cluster genes are produced as polycistronic RNA.[4]
See also
References
External links
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