Small nucleolar RNA U3
| U3 | |
|---|---|
snoRNA | |
| Domain(s) | Eukaryota; |
| PDB structures | PDBe |
In molecular biology, U3 snoRNA is a non-coding RNA found predominantly in the nucleolus. U3 has
snoRNAs; however, unlike other C/D box snoRNAs, it has not been shown to direct 2'-O-methylation
of other RNAs.
Rather, U3 is thought to guide site-specific cleavage of ribosomal RNA (rRNA) during pre-rRNA processing.[1]
The box C/D element is a subset of the six short sequence elements found in all U3 snoRNAs, namely boxes A, A', B, C, C', and D.rRNA processing functions of U3 snoRNA.
Species-specific secondary structure models
plants and basal eukaryotes have been proposed.[7]
See also
References
- PMID 17145781.
- PMID 9016512.
- PMID 10567566.
- PMID 9356246.
- PMID 15367679.
- ^ Srivastava A, Ahamad J, Ray AK, Kaur D, Bhattacharya A, Bhattacharya S (2014). Analysis of U3 snoRNA and small subunit processome components in the parasitic protist Entamoeba histolytica. Mol Biochem Parasitol. 193(2):82-92. doi: 10.1016/j.molbiopara.2014.03.001. Epub 2014 Mar 12
- S2CID 13055120.
External links
- Page for Small nucleolar RNA U3 at Rfam
- uRNADB: U3 page (archive)
- The UMASS snoRNAdb entry for U3
- The SGD entry for U3a
- The human snoRNAbase entry for U3
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