Small nucleolar RNA SNORD38
| Small nucleolar RNA SNORD38 | |
|---|---|
| SO | SO:0000593 |
| PDB structures | PDBe |
In
small nucleolar RNA
(snoRNA) and also often referred to as a guide RNA.
snoRNA U38 belongs to the
C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.[1]
U38 is located in introns 4 and 5 of ribosomal protein S8 in human and in the homologous genes in mouse and cow.[2] U38 is predicted to guides the methylation of 2'-O-ribose residues in 28S ribosomal RNA (rRNA). The mouse homologue of U38 (MBII-329) has also been identified.[3]
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External links
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