Small nucleolar RNA SNORD63
Small nucleolar RNA SNORD63 | |
---|---|
SO | SO:0000593 |
PDB structures | PDBe |
In
small nucleolar RNA
(snoRNA) and also often referred to as a guide RNA.
snoRNA U63 belongs to the
C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.[1]
snoRNA U63 was purified from HeLa cells by immunoprecipitation with antifibrillarin antibody. It is predicted to guide the 2'-O-ribose methylation of 28s ribosomal RNA (rRNA) at residue A4531.[2]
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