Trypanosome H/ACA box snoRNAs

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In

rRNA) and in some cases of small nuclear RNAs (sRNAs). These post-transcriptional modifications are crucial for rRNA processing, stability and maturation.[1]

H/ACA with pseudouridylation pocket

The H/ACA snoRNAs that guide pseudouridylation in Trypanosomes consist of a

Archea and Euglena.[2][3][4] The table below summarizes the H/ACA snoRNAs and the corresponding target sites identified in Trypanosomes.[5]

H/ACA snoRNAs identified in Trypanosomes

H/ACA ID Target Reference
TB3Cs2H1 ?308-L5 Myslyuk et al. 2008 [6]
TB3Cs2H2 ?1658-L5 Myslyuk et al. 2008 [6]
TB8Cs4H1 ?358-L3 Myslyuk et al. 2008 [6]
TB8Cs4H2 ?141-L3 Myslyuk et al. 2008[6]
TB9Cs6H1 ?199-L5, ?29-5.8S Myslyuk et al. 2008[6]
TB9Cs6H2 ?1653-L5 Myslyuk et al. 2008[6]
TB10Cs5H1 ?1254-L3 Myslyuk et al. 2008[6]
TB10Cs5H2 ?131-S Myslyuk et al. 2008[6]
TB10Cs5H3 ?1276-S Myslyuk et al. 2008[6]
TB11Cs5H1 ?1710-S Myslyuk et al. 2008[6]
TB11Cs5H2 ?176-L3 Myslyuk et al. 2008[6]
TB11Cs5H3 ?1314-L3 Myslyuk et al. 2008[6]
TB6Cs1H1 ?380-L3 Liang et al. 2005[7]
TB6Cs1H2 Liang et al. 2005[7]
TB6Cs1H3 ?662-S Liang et al. 2005[7]
TB6Cs1H4 ?824-L5 Liang et al. 2005[7]
TB6Cs2H1 ?1001-SSU Liang et al. 2005[7]
TB8Cs2H1 ?1113-S Liang et al. 2005[7]
TB8Cs3H1 ?1423-S Liang et al. 2005[7]
TB9Cs1H1 ?1088-S,?1272-L3 Liang et al. 2005[7]
TB9Cs1H2 ?1619-S Liang et al. 2005[7]
TB9Cs1H3 ?1250-L5 Liang et al. 2005[7]
TB9Cs2H1 ?617-L3 Liang et al. 2005[7]
TB9Cs2H2 ?1412-L5 Liang et al. 2005[7]
TB9Cs3H1 ?1208-L3 Liang et al. 2005[7]
TB9Cs3H2 ?1103-L5 Liang et al. 2005[7]
TB9Cs4H1 ?2123-S Liang et al. 2005[7]
TB9Cs4H2 ?1336-L3 Liang et al. 2005[7]
TB9Cs4H3 Liang et al. 2005[7]
TB10Cs1H1 ?659-L3 Liang et al. 2005[7]
TB10Cs1H2 ?901-L5 Liang et al. 2005[7]
TB10Cs1H3 ?40-S Liang et al. 2005[7]
TB10Cs2H1 ?1167-L3 Liang et al. 2005[7]
TB10Cs2H2 ?1173-L5 Liang et al. 2005[7]
TB10Cs3H1 ?263-S Liang et al. 2005[7]
TB10Cs3H2 ?397-L3 Liang et al. 2005[7]
TB10Cs4H1 ?2248-L5 Liang et al. 2005[7]
TB10Cs4H2 ?1186-S Liang et al. 2005[7]
TB10Cs4H3 ?1773-L5 Liang et al. 2005[7]
TB10Cs4H4 ?505-S Liang et al. 2005[7]
TB11Cs2H1 ?28 SL Liang et al. 2005[7]
TB11Cs3H1 ?1308-L3 Liang et al. 2005[7]
TB11Cs3H2 ?475-L3 Liang et al. 2005[7]
TB11Cs4H1 ?1357-L3 Liang et al. 2005[7]
TB11Cs4H2 ?566-L3 Liang et al. 2005[7]
TB11Cs4H3 ?61-S Liang et al. 2005[7]

References